“Twitter is worth more than a billion dollars,” insists Ron Conway. Conway, a Twitter investor and board member, Spark Capital’s Bijan Sabet and StockTwits backer Howard Lindzon dug into Twitter’s sky-high valuation during the 140Conf today. They also offered up predictions for where we’ll see the next wave of Twitter-related investments and acquisitions over the next six months:

—Is Twitter still interested in buying account management service CoTweet? Leaked internal documents showed that Twitter was doing due diligence for a potential CoTweet acquisition. “CoTweet just raised money—and I’m an investor—so obviously an acquisition didn’t happen,” Conway said. “CoTweet is pursuing an independent career now.”

—Extremely bullish on real-time search: “Real-time search will evolve into a multi-billion dollar opportunity,” Conway said. “The startups like OneRiot, CrowdEye and Scoopler are at the forefront, but I think we’ll see five really good companies emerge in the space that will validate it as well.” Conway added that he’d invested in a stealthy N.Y.-based startup that would monetize both Twitter’s new list features and real-time search.

—Twitter for finance: “Forget about going backstage at the Oscars or The Tonight Show; people need to get serious about the real changes we can make with Twitter,” Lindzon said. “CNBC has had the same 10 people talking about finance for the last decade – and clearly none of them know what they’re talking about. The next expert for investing in agriculture is probably sitting at home, with a real handle on how grain is going to trade; getting his commentary out through StockTwits – that’s the kind of democratization that Twitter is bringing to communication.”

—What are the most monetizable Twitter apps/clients? “I’ve tried half a dozen on the iPhone and some on the Blackberry, but I’m interested in apps that do more than just provide Twitter access,” Sabet said. “I think we’ll see much more interest in content curation and discovery apps that work with Twitter.”